Abstract for: Dynamics of Long-Term Essential Hypertension and Pharmacotherapy Options

Hypertension is a significant global health challenge as it is highly prevalent, causes comorbidities such as heart, brain, and kidney diseases, increases the risk of premature death and disability. Despite various treatment alternatives and global efforts, blood pressure control is insufficient worldwide. The suboptimal hypertension management is partially due to an incomplete understanding of the physiological mechanisms involved in blood pressure control. As a result of individual differentiation in hypertension pathophysiology optimal antihypertensive treatment strategies can vary for patients. Consequently, instead of one fits all treatments, personalized treatments can offer improved results on therapeutic goals.